She is possibly best known for her role as Dr. Izzie Stevens on ABC’s Grey’s Anatomy (2005-2010) for which she won a Primetime Emmy Award for Outstanding Supporting Actress – Drama Series in 2007. Heigl started her career as a child model with Wilhelmina Models before she turned her attention to acting. Heigl co-starred as Isabel Evans in the television series Roswell and movies including My Father the Hero before landing her break-out role in Grey’s Anatomy. Heigl was born in Washington, D.C., at Columbia Hospital for Women, the daughter of Nancy (née Engelhardt) – a personnel manager – and Paul Heigl, a financial executive and accountant. She is the youngest of four children (her siblings are Meg, Jason (deceased), and Holt). When Heigl was nine, an aunt visiting the family decided to take a number of photographs of her. Within a few weeks, Heigl was signed with Wilhelmina Models as a child model. Later that year, she starred in the horror film Bride of Chucky.

Oops! Stars’ Wardrobe Malfunctions Jennifer Lopez! Khloé Kardashian! Katherine Heigl?! See who’s showing a little too much skin [link]

Heigl co-starred as Isabel Evans in the television series Roswell and movies including My Father the Hero before landing her break-out role in Grey’s Anatomy. Heigl has established herself as a cover model appearing on numerous publications including Maxim, Vanity Fair and Cosmopolitan. in 1986, her older brother Jason died of injuries suffered in a car accident, after being thrown from the back of a pickup truck while out for lunch with some of his high school classmates. in 1995, she starred in the Steven Seagal action thriller Under Siege 2: Dark Territory. She took the lead role in Disney’s made-for-television film Wish Upon a Star in 1996, portraying two characters along with Danielle Harris. in 1999, Heigl turned her attention to television when she accepted the role of Isabel Evans on the science fiction TV drama Roswell, a role that was expanded in the show’s second and third seasons. in May 2006, Maxim awarded her #12 on their annual Hot 100List as well as voted the 19th “Sexiest Woman in the World” by readers of FHM magazine. After the attacks, Heigl recorded a public service announcement for the American Red Cross in an effort to help raise money for victims.